Background The rapidly increasing burden of noncommunicable diseases is a key determinant of global public health. Coronary artery disease (CAD) is the largest killer globally.

Objective To study the distribution and the effect of specific risk factors on Coronary Heart Disease in the adult population.

Study design Cross sectional study.

Sample size 1101 subjects.

Study area Rural and urban area of Lucknow District, Uttar Pradesh, India.

Study tool and Data collection Pre-designed and pre-tested interview in relation to smoking, passive tobacco smoking, alcohol consumption, physical activity, Blood pressure, BMI, central obesity, dietary history, mental status, diabetes, lipid profile was assessed.

Results The prevalence of coronary heart disease in the total study sample came out to be 7.1 %. The prevalence in urban was significantly higher than rural 8.8% and 3.8% respectively, CHD was higher in past smokers (17.8%) than nonsmokers (7.1%), passive tobacco smoking (10.7%), hypertensive subjects 11.2% as compared to normotensive subjects 5.5%, significant difference was found between overweight (M-9%, F-20.9%) and normal subjects (M-6.7%, F-6.8%), higher prevalence was observed among subjects having central obesity (M-8.6%, F-6.4%), Non vegetarian had higher CHD (9.9%) as compare to vegetarian (6.0%). CHD was more in subjects having mild depression (12.1%) than normal subjects (6.5%). The prevalence was higher in subjects having high total cholesterol (7.6%) and low HDL level (9.5%).

Conclusion CHD was higher in smokers, non vegetarian, hypertensive and depressive subjects. There was significant difference between Rural and Urban smokers. Passive tobacco smoking, Alcohol consumption, B.P, BMI, central obesity and overweight was significantly associated with CHD.