Article Text


Epidemiology and policy
P1-377 Trends and incidence of and mortality after first myocardial infarction in a national-wide cohort of men and women with diverse socioeconomic position and country of birth, 1987–2007
  1. D Yang,
  2. D Dzayee,
  3. O Beiki,
  4. L Alfredsson,
  5. U de Faire,
  6. T Moradi
  1. Karolinska Institutet, Stockholm, Sweden


Introduction Myocardial Infarction (MI) is a major cause of mortality and morbidity worldwide and one of the dominating burden of diseases in Sweden. We evaluated the incidence and survival of first MI in subgroups of social position and sex and compared immigrants with Sweden-born population.

Methods We followed a nation-wide cohort of more than seven million men and women ages 35 to 89 years through linkages between Swedish National Registers from 1987 to 2007. Incidence rate ratio (IRR) was estimated using Poisson regression. Of which, 347 834 non-fatal first MI patients were studied for their prognosis using Cox proportional hazard model.

Results and Conclusion We found immigrants from Southern Asia to Western Asia had higher and immigrants from Eastern and Southern-eastern Asia had lower risk of first MI than people born in Sweden. Within Europe, there seemed to be a slightly increasing risk trend from Southern and Western Europe to Eastern and Northern Europe. Low socioeconomic position was independent risk factor of first MI with education as the strongest predictor. However, we found occupation-based index might be more appropriate in immigrants study. Low education was also an independent risk factor for first MI survival. Both first MI risk and mortality decreased over the study period. Another novel finding was the surprisingly protective effect of with history of hyperlipidaemia or hypertension in the prognosis of first MI patients compared to those without.

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