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Trends in CVD
20-Year trends in major coronary risk factors in older British men: assessing the impact of medication use
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  1. S. L. Hardoon1,
  2. P. H. Whincup2,
  3. S. G. Wannamethee1,
  4. O. Papacosta1,
  5. M. C. Thomas1,
  6. L. T. Lennon1,
  7. A. G. Thomson1,
  8. S. Capewell3,
  9. R. W. Morris1
  1. 1
    Department of Primary Care & Population Health, Division of Population Health, UCL Medical School, University College London, Royal Free Campus, Rowland Hill Street, London, UK
  2. 2
    Department of Community Health Sciences, St George’s, University of London, Cranmer Terrace, London, UK
  3. 3
    School of Population Community & Behavioural Sciences, Division of Public Health, University of Liverpool, Whelan Building (3rd Floor), Brownlow Hill, Quadrangle, Liverpool, UK

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    Background

    Favourable trends in blood pressure (BP) and blood lipids have contributed to the falling incidence of coronary heart disease (CHD) in recent decades. The role of medication in the BP and blood lipid trends is unknown.

    Objectives

    To investigate the impact of medication on 20-year trends in BP and blood lipids in older British men.

    Design

    Longitudinal study.

    Setting

    24 British towns.

    Participants

    4231 men from a socially and geographically representative cohort of older British men, examined at baseline (1978–80, aged 40–59 years) and …

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