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Lifecourse obesity
Body mass index through life and adult mortality: results from the British 1946 birth cohort
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  1. B. H. Strand1,2,
  2. D. Kuh1,
  3. I. Shah1,
  4. J. Guralnik2,
  5. R. Hardy1
  1. 1
    MRC National Survey of Health and Development, MRC Unit for Lifelong Health and Ageing, 33 Bedford Place, London, UK
  2. 2
    Laboratory of Epidemiology, Demography, and Biometry National Institute on Aging, National Institutes of Health, Bethesda, MD, USA

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    Background

    Adult body mass index (BMI) has been consistently related to mortality, but little is known about the impact of earlier life BMI on adult mortality.

    Objective

    Investigate the impact of childhood, adolescent and early adult BMI on premature adult mortality and assess whether any associations are explained by adult BMI.

    Design

    Cohort study with prospective information on BMI at ages 2, 4, 6, 7, 11, 15, 20, 26 and 36 years, and …

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