Article Text

Download PDFPDF
Assuring effective malaria treatment in Africa: drug efficacy is necessary but not sufficient
  1. D N Durrheim1,
  2. H A Williams2
  1. 1Public Health and Tropical Medicine, James Cook University, Townsville, Australia; Hunter Population Health, Hunter New England Health, New South Wales, Australia
  2. 2Malaria Epidemiology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
  1. Correspondence to:
 Professor D N Durrheim
 School of Public Health and Tropical Medicine, James Cook University, Townsville, 4811, Australia; David.Durrheimjcu.edu.au

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Malaria must be tackled as an economic and social issue.

Resistance of Plasmodium falciparum parasites to antimalarial drugs has fuelled an increase in malaria prevalence and malaria specific mortality during the past decade in sub-Saharan Africa.1 Promising efficacy results from field trials of artemisinin containing combination therapy (ACT) are a source of optimism and numerous African countries are considering changing first line malaria drug policy to ACT to counter high levels of resistance.2 However, demonstrated drug efficacy is not enough to guarantee effective malaria treatment in Africa.3 Delivery of effective malaria treatment will not occur unless attention is also focused on the broader socio-cultural, economic, technical, and political environments in which it will be implemented.

Malaria is associated with retarded economic development in Africa and results in annual direct and indirect costs estimated to exceed US$2 billion.4 Intersectoral competition for resources in African countries is severe and social expenditure often receives a disproportionately small budgetary allocation. Within the health sector, the AIDS pandemic has placed an additional burden on limited health resources and, thus, resources available for malaria management are effectively shrinking.5 This is occurring at a time when …

View Full Text

Linked Articles