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Childhood cancers and atmospheric carcinogens
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  • Published on:
    Re: Atmospheric carcinogens and childhood cancers -- Environmental Tobacco Smoke should be included

    Dear Editor,

    Environmental smoke may also induce testosterone production in women and their fetuses. This has been demonstrated in female rats and their fetuses.

    Nicotine Tob Res. 2003 Jun;5(3):369-74.

    Epidemiological studies have shown that smoking during pregnancy markedly increases the risk for future tobacco use by adolescent female offspring. It has been hypothesized that the increas...

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    Conflict of Interest:
    None declared.
  • Published on:
    Half of cases

    Dear Editor,

    We are greatly disappointed to see the strange wording of the article by Prof E G Knox "Childhood cancers and atmospheric carcinogens", J. Epidemiol. Community Health [1], which says that "[t]he case material was extracted from a file of all 22 458 deaths from leukaemia or other cancer occurring before the 16th birthday in Great Britain between 1953 and 1980. They were classified into 11 main groups...

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    Conflict of Interest:
    None declared.
  • Published on:
    This could be due to induced testosterone...
    Dear Editor,

    This report may be explained by increased maternal testosterone as a result of exposure to these chemicals, especially nitrogen dioxide.

    In 2004, I wrote "Negative Effects of Nitrogen Dioxide May be due to Testosterone".

    (http:/...

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    Conflict of Interest:
    None declared.
  • Published on:
    Atmospheric carcinogens and childhood cancers -- Environmental Tobacco Smoke should be included

    Dear Editor,

    Professor Knox has provided a valuable analysis on atmospheric carcinogens and their association with childhood cancers. Omitted, however, was a major source of air pollution, environmental tobacco smoke (ETS), which contains many of the same carcinogens mentioned such as benzene, benz(a)pyrene, [1,3] butadiene, cadmium and arsenic. ETS exposure, particularly in utero, due to smoking by either pare...

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    Conflict of Interest:
    None declared.