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Excess in cardiovascular events on Mondays: could atherosclerotic plaques be more vulnerable after the weekend because of alcohol related cytokine dysregulation?
  1. Viktor Čulić
  1. Division of Cardiology, Department of Medicine, University Hospital Split, Šoltanska 1, 21000 Split, Croatia;

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    Barnett and Dobson performed meta-analysis of data about weekly distribution of cardiovascular events and found a slight excess in events on Mondays, more pronounced in men or associated with greater alcohol consumption.1 However, a debate about the underlying mechanisms is wide open.

    The meta-analysis provided little evidence to support the possibility that registration data collection or recording procedures play a significant part in the phenomenon. Another part of the hypothesis lies in regard to increased stress on Mondays, particularly in employed people. A …

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