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Siblings and adult mortality and stroke risk
  1. Piet Hein Jongbloet
  1. Department of Epidemiology and Biostatistics, University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, Netherlands; p.jongbloet@epib.umcn.nl

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    In men born between 1906 and 1938 and screened between 1970 and 1973 a strong relation between greater number of siblings and mortality risks was found by Hart and Davey Smith. These risks, however, were also related to adverse behavioural socioeconomic and health measures.1

    A great number of children, particularly in lower socioeconomic classes and in the earlier decades of the previous century, implies reproduction at earlier and more advanced maternal age and shorter interpregnancy intervals. These aspects have been neglected in studies on number of siblings in …

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