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Responses to a fourth dose of Haemophilus influenzae type B conjugate vaccine in early life
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  1. M H Slack,
  2. D Schapira,
  3. R J Thwaites,
  4. M Burrage,
  5. J Southern,
  6. D Goldblatt,
  7. E Miller

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    Objective:

    To describe the immune response of preterm infants, with a reduced response to primary Haemophilus influenzae type B (Hib) immunisation, to a fourth dose of Hib conjugate vaccine given in early life.

    Design:

    Prospective observational study.

    Setting:

    Five Wessex Neonatal Units.

    Patients:

    Infants born at < 32 weeks and immunised with three doses of combined …

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