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The many causes of human despair, La Ramblas, Barcelona
  1. Centre for Research in Primary Care, Nuffield Institute for Health, University of Leeds, 71–75 Clarendon Street, Leeds LS2 9PL, UK (r.d.neal{at}

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    Whether it was homelessness, addiction, marital disharmony, physical ill health, bereavement, stressful work, or the loss of a football match that caused this man's despair, the observer cannot tell. What is certain though, is that he was equally as oblivious of the many passers by, as they were of him.