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The relation between cholesterol and haemorrhagic or ischaemic stroke in the Renfrew/Paisley study
  1. Carole L Harta,
  2. David J Holeb,
  3. George Davey Smithc
  1. aDepartment of Public Health, University of Glasgow, 1 Lilybank Gardens, Glasgow G12 8RZ, bWest of Scotland Cancer Surveillance Unit, Department of Public Health, University of Glasgow, cDepartment of Social Medicine, University of Bristol
  1. Carole Hart (c.l.hart{at}

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Studies have found little association between cholesterol and overall stroke risk, but this could be attributable to different relations for haemorrhagic and ischaemic stroke. Stroke mortality data from prospective studies cannot usually be divided into stroke subtypes. We have therefore analysed stroke based on hospital admissions, obtained by computerised linkage with acute hospital discharges in Scotland for a large prospective cohort study.

Methods and Results

The Renfrew/Paisley study was carried out between 1972 and 1976 involving 15 406 residents aged 45–64 from the towns of Renfrew and Paisley.1 The linkage provided records of all main diagnoses of stroke in a 20 year follow up period. There was no information on participants having strokes and not being admitted to hospital, but with this relatively young age group, most would be admitted. Blood samples were taken for the measurement of plasma cholesterol, measured in …

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  • Funding: this study was provided with grants from Chest, Heart and Stroke Scotland, and the Stroke Association.

  • Conflicts of interest: none.