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A randomized controlled trial of vitamin C in the prevention and amelioration of the common cold.
  1. P C Elwood,
  2. H P Lee,
  3. A S St Leger,
  4. M Baird,
  5. A N Howard


    A randomized controlled trial of the effect of 1 g ascorbic acid per day in the prevention of the common cold was conducted on 688 adult women. There is evidence of a small reduction by vitamin C in the mean number of chest colds, but no evidence of any effect on simple colds. The existence of a subgroup of vulnerable women in the community who benefit from vitamin C was considered but further examination of the data gives no support to this conclusion.

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