User profiles for "author:Wade V Welshons"

Wade V. Welshons

University of Missouri, Biomedical Sciences
Verified email at missouri.edu
Cited by 23707

Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses

LN Vandenberg, T Colborn, TB Hayes… - Endocrine …, 2012 - academic.oup.com
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

Human exposure to bisphenol A (BPA)

LN Vandenberg, R Hauser, M Marcus, N Olea… - Reproductive …, 2007 - Elsevier
The plastic monomer and plasticizer bisphenol A (BPA) is one of the highest volume
chemicals produced worldwide. BPA is used in the production of polycarbonate plastics and …

Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure

WV Welshons, SC Nagel, FS vom Saal - Endocrinology, 2006 - academic.oup.com
Over 6 billion pounds per year of the estrogenic monomer bisphenol A (BPA) are used to
manufacture polycarbonate plastic products, in resins lining metal cans, in dental sealants …

Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses

FS Saal, BG Timms, MM Montano… - Proceedings of the …, 1997 - National Acad Sciences
On the basis of results of studies using high doses of estrogens, exposure to estrogen during
fetal life is known to inhibit prostate development. However, it is recognized in endocrinology …

Large effects from small exposures. I. Mechanisms for endocrine-disrupting chemicals with estrogenic activity.

WV Welshons, KA Thayer, BM Judy… - Environmental …, 2003 - ehp.niehs.nih.gov
Information concerning the fundamental mechanisms of action of both natural and
environmental hormones, combined with information concerning endogenous hormone …

Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol.

SC Nagel, FS vom Saal, KA Thayer… - Environmental …, 1997 - ehp.niehs.nih.gov
We have developed a relative binding affinity-serum modified access (RBA-SMA) assay to
determine the effect of serum on the access of xenoestrogens to estrogen receptors within …

[HTML][HTML] Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement

JP Myers, MN Antoniou, B Blumberg, L Carroll… - Environmental …, 2016 - Springer
The broad-spectrum herbicide glyphosate (common trade name “Roundup”) was first sold to
farmers in 1974. Since the late 1970s, the volume of glyphosate-based herbicides (GBHs) …

A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior

FS Vom Saal, PS Cooke… - Toxicology and …, 1998 - journals.sagepub.com
Two chemicals previously shown to have estrogenic activity, bisphenol A and octylphenol,
were examined for their effects on accessory reproductive organs and daily sperm …

Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of …

FS Vom Saal, BT Akingbemi, SM Belcher… - Reproductive …, 2007 - Elsevier
This document is a summary statement of the outcome from the meeting:“Bisphenol A: An
Examination of the Relevance of Ecological, In vitro and Laboratory Animal Studies for …

Bisphenol A data in NHANES suggest longer than expected half-life, substantial nonfood exposure, or both

RW Stahlhut, WV Welshons… - Environmental health …, 2009 - ehp.niehs.nih.gov
Background It is commonly stated in the literature on human exposure to bisphenol A (BPA)
that food is the predominant BPA exposure source, and that BPA is rapidly and completely …