User profiles for "author:Christian Stock"
Christian StockSenior Principal Statistician, Boehringer Ingelheim Verified email at boehringer-ingelheim.com Cited by 7127 |
Effect of screening sigmoidoscopy and screening colonoscopy on colorectal cancer incidence and mortality: systematic review and meta-analysis of randomised …
H Brenner, C Stock, M Hoffmeister - Bmj, 2014 - bmj.com
Objectives To review, summarise, and compare the evidence for effectiveness of screening
sigmoidoscopy and screening colonoscopy in the prevention of colorectal cancer …
sigmoidoscopy and screening colonoscopy in the prevention of colorectal cancer …
[HTML][HTML] Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp
KO Alfarouk, CM Stock, S Taylor, M Walsh… - Cancer cell …, 2015 - Springer
Cancer chemotherapy resistance (MDR) is the innate and/or acquired ability of cancer cells
to evade the effects of chemotherapeutics and is one of the most pressing major dilemmas in …
to evade the effects of chemotherapeutics and is one of the most pressing major dilemmas in …
Role of ion channels and transporters in cell migration
A Schwab, A Fabian, PJ Hanley… - Physiological …, 2012 - journals.physiology.org
Cell motility is central to tissue homeostasis in health and disease, and there is hardly any
cell in the body that is not motile at a given point in its life cycle. Important physiological …
cell in the body that is not motile at a given point in its life cycle. Important physiological …
Reduced risk of colorectal cancer up to 10 years after screening, surveillance, or diagnostic colonoscopy
H Brenner, J Chang–Claude, L Jansen, P Knebel… - Gastroenterology, 2014 - Elsevier
Background & Aims Data from randomized controlled trials on the effects of screening
colonoscopies on colorectal cancer (CRC) incidence and mortality are not available …
colonoscopies on colorectal cancer (CRC) incidence and mortality are not available …
Multiparametric magnetic resonance imaging (MRI) and MRI–transrectal ultrasound fusion biopsy for index tumor detection: correlation with radical prostatectomy …
JP Radtke, C Schwab, MB Wolf, MT Freitag, CD Alt… - European urology, 2016 - Elsevier
Background Multiparametric magnetic resonance imaging (mpMRI) and MRI fusion targeted
biopsy (FTB) detect significant prostate cancer (sPCa) more accurately than conventional …
biopsy (FTB) detect significant prostate cancer (sPCa) more accurately than conventional …
Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts
L Schneider, M Cammer, J Lehman… - Cellular physiology and …, 2010 - karger.com
Cell motility and migration play pivotal roles in numerous physiological and
pathophysiological processes including development and tissue repair. Cell migration is …
pathophysiological processes including development and tissue repair. Cell migration is …
Protons make tumor cells move like clockwork
C Stock, A Schwab - Pflügers Archiv-European Journal of Physiology, 2009 - Springer
Cancer accounts for 13% of the yearly total mortality worldwide. Most cancer deaths are the
sequel of metastatic diseases rather than of primary tumor growth. Thus, the major challenge …
sequel of metastatic diseases rather than of primary tumor growth. Thus, the major challenge …
[HTML][HTML] Why rankings of biomedical image analysis competitions should be interpreted with care
International challenges have become the standard for validation of biomedical image
analysis methods. Given their scientific impact, it is surprising that a critical analysis of …
analysis methods. Given their scientific impact, it is surprising that a critical analysis of …
Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange
C Stock, B Gassner, CR Hauck, H Arnold… - The Journal of …, 2005 - Wiley Online Library
Their glycolytic metabolism imposes an increased acid load upon tumour cells. The surplus
protons are extruded by the Na+/H+ exchanger (NHE) which causes an extracellular …
protons are extruded by the Na+/H+ exchanger (NHE) which causes an extracellular …
[HTML][HTML] Proton channels and exchangers in cancer
EP Spugnini, P Sonveaux, C Stock… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Although cancer is characterized by an intratumoral genetic heterogeneity, a totally
deranged pH control is a common feature of most cancer histotypes. Major determinants of …
deranged pH control is a common feature of most cancer histotypes. Major determinants of …