This report describes the physics case, the resulting detector requirements, and the evolving
detector concepts for the experimental program at the Electron-Ion Collider (EIC). The EIC …

Investigation into the mechanism of cytokine signaling led to the discovery of the JAK/STAT
pathway. Following the binding of cytokines to their cognate receptor, signal transducers …

This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …

Background The spread of antibiotic-resistant bacteria poses a substantial threat to
morbidity and mortality worldwide. Due to its large public health and societal implications …

Background Enzalutamide is an oral androgen-receptor inhibitor that prolongs survival in
men with metastatic castration-resistant prostate cancer in whom the disease has …

Early-onset, severe retinal dystrophy caused by mutations in the gene encoding retinal
pigment epithelium–specific 65-kD protein (RPE65) is associated with poor vision at birth …

Ghrelin is a novel growth hormone-releasing peptide, originally identified in the rat stomach
as the endogenous ligand for the growth hormone secretagogue-receptor (GHS-R1a) …

Autosomal dominant optic atrophy (ADOA) is the most prevalent hereditary optic neuropathy
resulting in progressive loss of visual acuity, centrocoecal scotoma and bilateral temporal …

Bone marrow–derived stromal cells (BMSCs) protect against acute lung injury (ALI). To
determine the role of BMSC mitochondria in this protection, we airway-instilled mice first with …

This paper assumes that outside investors have imperfect information about firms'
profitability and that cash dividends are taxed at a higher rate than capital gains. It is shown …