Health professionals are encouraged to take the Guidelines fully into account when
exercising their clinical judgment, as well as in the determination and the implementation of …

Objectives: To develop evidence-based EULAR recommendations for cardiovascular (CV)
risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and …

Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

Background Sodium–glucose cotransporter 2 inhibitors reduce the risk of hospitalization for
heart failure in patients with heart failure and a reduced ejection fraction, but their effects in …

Background Overweight and obesity are increasing worldwide. To help assess their
relevance to mortality in different populations we conducted individual-participant data meta …

Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of
hospitalization for heart failure in patients regardless of the presence or absence of …

ESC Guidelines 3039 administrative staff and by the referees and supervisory committees of
the two organizations. It is our hope that this huge effort has generated guidelines that will …

We expanded GWAS discovery for type 2 diabetes (T2D) by combining data from 898,130
European-descent individuals (9% cases), after imputation to high-density reference panels …

Background Although diabetes has been associated with COVID-19-related mortality, the
absolute and relative risks for type 1 and type 2 diabetes are unknown. We assessed the …

Background Diabetes has been associated with increased COVID-19-related mortality, but
the association between modifiable risk factors, including hyperglycaemia and obesity, and …