User profiles for "author:Consolato Sergi"
Consolato SergiChildren's Hospital of Eastern Ontario, University of Ottawa, ON, Canada Verified email at cheo.on.ca Cited by 21930 |
[HTML][HTML] DNA damage response revisited: the p53 family and its regulators provide endless cancer therapy opportunities
Y Abuetabh, HH Wu, C Chai, H Al Yousef… - … & molecular medicine, 2022 - nature.com
Antitumor therapeutic strategies that fundamentally rely on the induction of DNA damage to
eradicate and inhibit the growth of cancer cells are integral approaches to cancer therapy …
eradicate and inhibit the growth of cancer cells are integral approaches to cancer therapy …
Giardiasis: an overview
AKC Leung, AAM Leung, AHC Wong… - Recent patents on …, 2019 - ingentaconnect.com
Background: Giardiasis is an important cause of waterborne and foodborne diarrhea,
daycare center outbreaks, and traveler's diarrhea. Objective: The study aimed to provide an …
daycare center outbreaks, and traveler's diarrhea. Objective: The study aimed to provide an …
[HTML][HTML] Insulin growth factor binding protein 7 (IGFBP7)-related cancer and IGFBP3 and IGFBP7 crosstalk
L Jin, F Shen, M Weinfeld, C Sergi - Frontiers in Oncology, 2020 - frontiersin.org
The insulin/insulin-like growth factors (IGFs) have crucial tasks in the growth, differentiation,
and proliferation of healthy and pernicious cells. They are involved in coordinated …
and proliferation of healthy and pernicious cells. They are involved in coordinated …
Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture
Genes associated with human microcephaly, a condition characterized by a small brain,
include critical regulators of proliferation, cell fate and DNA repair. We describe a syndrome …
include critical regulators of proliferation, cell fate and DNA repair. We describe a syndrome …
Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority …
CJ Portier, BK Armstrong, BC Baguley… - J Epidemiol …, 2016 - jech.bmj.com
The International Agency for Research on Cancer (IARC) Monographs Programme identifies
chemicals, drugs, mixtures, occupational exposures, lifestyles and personal habits, and …
chemicals, drugs, mixtures, occupational exposures, lifestyles and personal habits, and …
Mucosal barrier depletion and loss of bacterial diversity are primary abnormalities in paediatric ulcerative colitis
M Alipour, D Zaidi, R Valcheva, J Jovel… - Journal of Crohn's …, 2016 - academic.oup.com
Abstract Background and Aims: Ulcerative colitis [UC] is associated with colonic mucosa
barrier defects and bacterial dysbiosis, but these features may simply be the result of …
barrier defects and bacterial dysbiosis, but these features may simply be the result of …
[HTML][HTML] Unfermented β-fructan fibers fuel inflammation in select inflammatory bowel disease patients
Background & aims Inflammatory bowel diseases (IBD) are affected by dietary factors,
including nondigestible carbohydrates (fibers), which are fermented by colonic microbes …
including nondigestible carbohydrates (fibers), which are fermented by colonic microbes …
Pyridoxine-responsive seizures as the first symptom of infantile hypophosphatasia caused by two novel missense mutations (c. 677T> C, p. M226T; c. 1112C> T, p …
S Baumgartner-Sigl, E Haberlandt, S Mumm… - Bone, 2007 - Elsevier
Pyridoxine-responsive seizures (PRS) and the role of pyridoxine (PN, vitamin B6) in
hypophosphatasia (HPP) are incompletely understood. Typically, PRS and HPP are rare …
hypophosphatasia (HPP) are incompletely understood. Typically, PRS and HPP are rare …
Glucose Is Involved in the Dynamic Regulation of m6A in Patients With Type 2 Diabetes
Y Yang, F Shen, W Huang, S Qin… - The Journal of …, 2019 - academic.oup.com
Abstract Context N 6-methyladenosine (m6A) in mRNA is the most abundant and reversible
modification. However, the mechanism behind the decrease in m6A in patients with type 2 …
modification. However, the mechanism behind the decrease in m6A in patients with type 2 …
Carcinogenicity of aspartame, methyleugenol, and isoeugenol
E Riboli, FA Beland, DW Lachenmeier… - The Lancet …, 2023 - thelancet.com
In June, 2023, a Working Group of 25 scientists from 12 countries met at the International
Agency for Research on Cancer (IARC) in Lyon, France, to finalise their evaluation of the …
Agency for Research on Cancer (IARC) in Lyon, France, to finalise their evaluation of the …