[Role of antiretroviral therapy in the reduction of the association between low educational level and AIDS-related mortality]

Med Clin (Barc). 2008 Feb 9;130(4):133-5. doi: 10.1157/13115769.
[Article in Spanish]

Abstract

Background and objective: AIDS-related mortality has been classically associated with lowest socioeconomic groups. In Spain, the highly active antiretroviral therapy (HAART) is delivered without cost; therefore this treatment it should have reduced the great social inequalities in AIDS-mortality seen before the HAART era. This study aims to assess the absolute and relative socioeconomic differences in AIDS-mortality in the Region of Madrid after the introduction of HAART.

Patients and method: Two twenty-months cohorts were created, in 1996 and 2001, which correspond to an early and late HAART-era respectively. Absolute and relative differences in the AIDS-mortality rates were calculated for both periods using generalized linear models.

Results: Absolute differences between the lowest and highest education level AIDS-related deaths decreased around 70% in the 2001 cohort. Those with lowest education level achieved the highest reduction rate, hence relative differences descended as well.

Conclusions: HAART has had an essential role in decreasing social inequalities in AIDS-mortality.

Publication types

  • English Abstract

MeSH terms

  • Acquired Immunodeficiency Syndrome / drug therapy*
  • Acquired Immunodeficiency Syndrome / mortality*
  • Adult
  • Antiretroviral Therapy, Highly Active*
  • Cohort Studies
  • Educational Status
  • Female
  • Humans
  • Male
  • Middle Aged
  • Socioeconomic Factors
  • Spain
  • Urban Population