Gender, poverty and race, the "triple threat" referred to in the title, are three major risk factors that contribute to the high prevalence of weight-related problems in this country. Current psychological literature on weight management has generally ignored the effects of these variables and their implications for developing interventions for underserved populations which include women, minorities and poor people. The present paper discusses the literature on the effects of gender, race, and class on weight levels and associated psychosocial variables. Conclusions drawn illustrate that weight is a major issue for women, and that race and class also have effects on weight levels which can affect health status. Areas of further exploration and of action are identified to address problems that women face regarding weight.