Association of white blood cell count with suicide risk in the Korean Cancer Prevention Study (n=419 527)
| Number of suicides | Number at risk | Age adjustment | Multiple adjustment* | Multiple adjustment† | |
| Men | |||||
| Quartile 1 (<5.9)‡ | 237 | 24 828 | 1.0 (ref) | 1.0 | 1.0 |
| Quartile 2 (≥5.9 to <7.0) | 267 | 28 168 | 1.00 (0.84, 1.19) | 0.98 (0.82, 1.17) | 1.03 (0.86, 1.24) |
| Quartile 3 (≥7.0 to <8.2) | 229 | 26 416 | 0.93 (0.78, 1.12) | 0.91 (0.75, 1.09) | 0.91 (0.75, 1.11) |
| Quartile 4 (≥8.2) | 277 | 27 231 | 1.15 (0.97, 1.37) | 1.10 (0.92, 1.31) | 1.10 (0.91, 1.33) |
| P value for trend | – | – | 0.0852 | 0.2688 | 0.3212 |
| Women | |||||
| Quartile 1 (<5.4) | 201 | 76 280 | 1.0 (ref) | 1.0 | 1.0 |
| Quartile 2 (≥5.4 to <6.3) | 251 | 73 263 | 1.30 (1.08, 1.57) | 1.32 (1.09, 1.59) | 1.35 (1.11, 1.64) |
| Quartile 3 (≥6.3 to <7.4) | 282 | 81 350 | 1.31 (1.09, 1.57) | 1.32 (1.10, 1.58) | 1.34 (1.10, 1.62) |
| Quartile 4 (≥7.4) | 285 | 81 991 | 1.30 (1.09, 1.56) | 1.30 (1.08, 1.56) | 1.32 (1.09, 1.60) |
| P value for trend | – | – | 0.0195 | 0.0243 | 0.0248 |
| P value for interaction by gender | – | – | 0.4999 | 0.2714 | 0.2375 |
*Multiple adjustment is adjustment for: age, body mass index, smoking status, alcohol consumption, exercise, hypertension, diabetes and health insurance premium.
†Same variables as in prior statistical model but the analytical sample is based on exclusions of suicide deaths in the first 5 years of follow-up (893 suicide deaths in 95 364 men; 945 such deaths in 304 727 women).
‡White cell counts are multiples of 109 cells/L.