Table 2

Risk of high A1C level (≥6.5%) by weight status categories

BMI categoryA1C <6.5%
n (row %)
A1C ≥6.5%
n (row %)
RR (95% CI)P valueRD (95% CI)P value
All participants (n=5702)*
 Underweight105 (78.4%)29 (21.64%)3.6 (2.5 to 5.1)<0.000115.7% (8.6% to 22.7%)<0.0001
 Healthy weight1164 (67.8%)554 (32.3%)5.5 (4.6 to 6.3)<0.000126.3% (23.9% to 28.6%)<0.0001
 Overweight498 (75.5%)162 (24.6%)4.1 (3.4 to 5.0)<0.000118.6% (15.2% to 21.9%)
 Obese2999 (94.0%)191 (6.0%)RefRef
Children
 Ages 4–9 (n=1205)
  Underweight26 (76.5%)8 (23.5%)6.6 (3.2 to 13.7)<0.000120.0% (5.6% to 34.3%)0.0064
  Healthy weight302 (70.6%)126 (29.4%)8.2 (5.3 to 12.7)<0.000125.9% (21.3% to 30.4%)<0.0001
  Overweight92 (72.4%)35 (27.6%)7.7 (4.7 to 12.7)<0.000124.0% (16.1% to 31.9%)<0.0001
  Obese594 (96.4%)22 (3.6%)RefRef
Pre-teens
 Ages 10–12 (n=1194)
  Underweight17 (73.9%)6 (26.1%)8.7 (3.9 to 19.4)<0.000123.1% (5.1% to 41.1%)0.0118
  Healthy weight165 (61.1%)105 (38.9%)13.0 (8.5 to 20.0)<0.000135.9% (30.0% to 41.8%)<0.0001
  Overweight102 (77.9%)29 (22.1%)7.4 (4.4 to 12.4)<0.000119.2% (11.9% to 26.4%)<0.0001
  Obese747 (97.0%)23 (3.0%)RefRef
Teenagers
 Ages 13–19 (n=3303)
  Underweight62 (80.5%)15 (19.5%)2.4 (1.5 to 3.9)0.000311.4% (2.5% to 20.3%)0.0125
  Healthy weight697 (68.3%)323 (31.7%)3.9 (3.3 to 4.7)<0.000123.6% (20.5% to 26.7%)<0.0001
  Overweight304 (75.6%)98 (24.4%)3.0 (2.4 to 3.8)<0.000116.3% (11.9% to 20.7%)<0.0001
  Obese1658 (91.9%)146 (8.1%)RefRef
  • Weight status definitions via BMI percentiles with underweight = <5th, healthy weight = 5th to <85th, overweight = 85th to <95th and obese ≥95th.

  • *Crude results for all participants are reported here, even though there is a statistically significant interaction between age and weight status category (P value<0.0001).

  • BMI, body mass index; RD, risk difference; Ref, reference category; RR, relative risk.