Table 1

Studies investigating associations between neighbourhood-level socioeconomic factors and cardiovascular disease mortality

ReferenceAge of participants, yearsSettingArea or neighbourhood socioeconomic measure usedRelative risks (95% CI)
Smith et al445–64Renfrew and Paisley, ScotlandCarstairs deprivation score (based on male unemployment, overcrowding, car ownership, proportion in social classes IV and V)HR for most deprived vs least deprived categories
1.26 (1.04 to 1.52) for men
1.33 (1.05 to 1.69) for women
Waitzman and Smith925–74USA—National Health and Nutrition
Examination Survey
Federally defined poverty areas of residence based on census tractsRR for poverty-area vs non-poverty area
1.90 (1.24 to 2.90) in 25–54 years
0.83 (0.66 to 1.03) in 55–74 years
Diez Roux et al5≥65USA—Forsyth Co, North Carolina; Washington Co, Maryland; Sacramento Co, California and Pittsburgh, PennsylvaniaNeighbourhood deprivation score based on census (household income, value of housing units, education and occupation)HR for most vs least disadvantaged tertiles
1.5 (1.2 to 1.9) in Caucasian participants
1.2 (0.7 to 2.2) in African–American participants
Borrell et al345–64USA—Forsyth County, North Carolina; Jackson, Mississippi; the northwestern suburbs of Minneapolis, Minnesota; and Washington County, MarylandNeighbourhood deprivation score based on census (household income, value of housing units, education and occupation)HR for most vs least disadvantaged tertiles
1.4 (1.0 to 2.0) in Caucasian participants
1.1 (0.8 to 1.6) in African-American participants
Steenland et al850–74USA—Cancer Prevention Study II Nutrition CohortArea-level socioeconomic status based on census data including household income, home value, occupation and educationRR for lowest vs highest area-level score group
1.46 (1.22 to 1.74) for men
1.33 (1.00 to 1.77) for women
Major et al650–71USA—California, Florida, Louisiana, New Jersey, North Carolina, Pennsylvania, Atlanta (Georgia) and Detroit (Michigan)Neighbourhood deprivation index based on census data (housing, residential stability, poverty, employment, occupation, racial composition, education)HR for highest vs lowest deprivation quintile
1.33 (1.19 to 1.49) for men
1.18 (1.01 to 1.38) for women
Sanchez-Santos et al760–7924 British townsIndex of multiple deprivation (income, employment, barriers to services, living environment)HR per SD increase in deprivation score
1.22 (1.09 to 1.37) in women
Chan et al 201412All agesUSA—458 countiesCommunity characteristics including US census dataEstimated increase in death per 100 000 from 25th to 75th centile—for education 19.92 (14.12 to 25.80); 16.06 (10.77 to 21.45) for employment in construction
  • HR, hazard ratio; RR, rate ratio.