Table 1

Baseline characteristics of the women enrolled in the Aberdeen folic acid supplementation trial 1966–1967 (n=2928)

 Placebo (n=1977)Folic acid supplement (mg/day)
0.2 (n=466)5 (n=485)*
Age (years)*26.0 (5.6)25.8 (5.5)25.5 (5.2)
Gestational age at booking (weeks)17.5 (5.3)16.9 (4.8)17.7 (5.6)
Weight at booking (kg)†59.6 (9.5)59.0 (8.9)59.6 (9.1)
Height (cm)‡159.5 (5.9)159.4 (6.4)159.5 (6.1)
Smoked at booking, n (%)§840 (45.8)188 (42.2)203 (44.7)
Social class code, n (%)¶
 I122 (6.2)31 (6.7)34 (7.0)
 II219 (11.1)44 (9.4)49 (10.1)
 IIIN204 (10.3)61 (13.1)63 (13.0)
 IIIM768 (38.8)170 (36.5)146 (29.9)
 IV330 (16.7)70 (15.0)91 (18.8)
 V164 (8.3)43 (9.2)44 (9.1)
 Undefined or armed forces170 (8.6)47 (10.1)59 (12.2)
Parity, n (%)
 0734 (37.1)198 (42.5)196 (40.4)
 1–3904 (45.7)216 (46.4)224 (46.2)
 ≥4339 (17.1)52 (11.2)65 (13.4)
  • Values are mean±SD.

  • Adapted with copyright permission from Charles et al.28

  • *Age available for 2868 (98%) women.

  • †Weight at booking available for 2813 (96.1%) women.

  • ‡Height available for 2860 (97.7%) women.

  • §Smoking status at booking available for 2734 (93.4%) women.

  • ¶Based on the husband's or partner's occupation at the time of delivery.