Table 3

Adjusted ORs for maternal pre-pregnancy obesity and adolescents' wheeze at age 15 years, stratified by parental history of atopy

Factors	Adjusted^* OR (95% CI), p Value
	Ever wheeze		Current wheeze
	No parental atopy	Parental atopy	No parental atopy	Parental atopy
Maternal pre-pregnancy weight^† (n=8874)
First tertile 35–54 kg	Reference	Reference	Reference	Reference
Second tertile 55–61 kg	1.27 (0.95 to 1.68), p=0.10	0.95 (0.74 to 1.22), p=0.70	1.78^‡ (1.20 to 2.64), p=0.004	0.97 (0.69 to 1.37), p=0.88
Third tertile 62–130 kg	1.51^‡ (1.13 to 2.02), p=0.005	1.02 (0.80 to 1.31), p=0.87	2.00^‡ (1.34 to 2.98), p=0.001	1.25 (0.90 to 1.74), p=0.19
Maternal pre-pregnancy BMI (n=8838)
19–24.9 (normal)	Reference	Reference	Reference	Reference
<19 (underweight)	2.19^‡ (1.19 to 4.02), p=0.012	1.08 (0.73 to 1.61), p=0.70	1.88 (0.86 to 4.12), p=0.11	0.99 (0.59 to 1.66), p=0.97
25–29.9 (overweight)	2.97^‡ (1.52 to 5.82), p=0.001	1.13 (0.71 to 1.81), p=0.61	2.17 (0.91 to 5.18), p=0.08	1.12 (0.61 to 2.06), p=0.72
≥30 (obese)	3.51^‡ (1.60 to 7.68), p=0.002	0.59 (0.28 to 1.27), p=0.18	4.03^‡ (1.54 to 10.54), p=0.004	1.02 (0.41 to 2.49), p=0.97

↵* Adjusted for social class at birth, marital status at birth, maternal education, maternal asthma, birth weight, parental smoking during gestation, and adolescent BMI at age 15 years.
↵† Tertile cut-offs, calculated from the whole-study population.
↵‡ 95% CI for OR significant at least at p<0.05.