Table 5

Hazard rate ratios and 95% CIs for the association between ASD and assisted conception combined and divided into IVF and OI according to specific hormones*

Assisted conception, allAssisted conception, boysAssisted conception, girlsIVF, allOI, all
Downregulation0.82 (0.49 to 1.37)0.79 (0.45 to 1.40)0.93 (0.29 to 2.92)0.57 (0.28 to 1.16)1.09 (0.48 to 2.51)
FSH1.44 (1.16 to 1.80)1.32 (1.02 to 1.70)1.99 (1.23 to 3.18)1.73 (1.10 to 2.71)1.29 (0.89 to 1.89)
hCG1.28 (1.05 to 1.55)1.16 (0.93 to 1.44)1.85 (1.23 to 2.77)1.37 (0.87 to 2.15)1.17 (0.79 to 1.71)
Clomiphene1.14 (0.93 to 1.40)1.02 (0.80 to 1.29)1.75 (1.15 to 2.65)1.34 (0.54 to 3.32)0.82 (0.53 to 1.28)
  • * Reference: natural conception, adjusted for maternal age, education, parity, smoking, body weight and multiplicity.

  • ASD, autism spectrum disorders; FSH, follicle stimulating hormone; hCG, human chorionic gonadotropin; IVF, in vitro fertilisation; OI, ovulation induction.