Table 2

 Adjusted* prevalence OR and 95% CI of learning disability by category of seven persistent organic pollutants

POPsDetection rate (%)Non-detectable POPsDetectable POPsp Value
POP, persistent organic pollutant.
*Adjustment for age, race/ethnicity, sex, poverty index ratio, mother’s age at pregnancy, cigarette smoking during pregnancy, birth weight, body mass index and saturated fat intake.
†Median (interquartile range).
3,3′,4,4′,5-penta chlorobiphenyl22.4Concentration (ng/g of lipid)†9.1 (6.7–20.6)
Cases/n33/20811/69
Prevalence (%)15.915.9
Adjusted* OR (95% CI)Referent1.26 (0.47 to 3.32)0.62
1,2,3,4,6,7,8-hepta chlorodibenzo-p-dioxin30.5Concentration (pg/g of lipid)†38.9 (30.2–50.9)
Cases/n24/19120/86
Prevalence (%)12.623.3
Adjusted* OR (95% CI)Referent2.08 (1.17 to 3.68)0.02
1,2,3,4,6,7,8,9-octa chlorodibenzo-p-dioxin26.8Concentration (pg/g of lipid)†23.0 (18.5–30.2)
Cases/n24/19920/78
Prevalence (%)12.125.6
Adjusted* OR (95% CI)Referent2.72 (1.24 to 5.99)0.02
1,2,3,4,6,7,8-hepta chlorodibenzofuran31.9Concentration (pg/g of lipid)†10.0 (7.8–14.8)
Cases/n23/18921/88
Prevalence (%)12.223.9
Adjusted* OR (95% CI)Referent2.18 (1.15 to 4.15)0.02
β-hexachlorocyclo-hexane22.4Concentration (ng/g of lipid)†17.9 (14.6–26.4)
Cases/n38/2016/76
Prevalence (%)18.97.9
Adjusted* OR (95% CI)Referent0.37 (0.13 to 1.02)0.05
Trans-nonachlor25.4Concentration (ng/g of lipid)†10.9 (8.4–16.0)
Cases/n27/20717/70
Prevalence (%)13.024.3
Adjusted* OR (95% CI)Referent1.67 (0.46 to 6.14)0.41
Detectable<50thDetectable⩾50th
p,p′-dichlorodiphenyl trichloroethane100Concentration (ng/g of lipid)†75.3 (49.0–98.4)278 (186–528)
Cases/n26/13818/139
Prevalence (%)18.813.0
Adjusted* OR (95% CI)Referent0.89 (0.24 to 3.37)0.85