Table 1

 Description of the studies included in the review*

PaperPublication yearCost countryAge range (mean)Modelling†Prevention category‡Treatment durationDiscount factor (%)Funding source
*In total 24 studies were included in the final analysis. †Primary: based on observations from a randomised trial. Secondary: based on expectations from a theoretical model. ‡Secondary prevention is among patients with clinical coronary heart disease or cardiovascular disease, primary prevention among apparently healthy persons.
Ashraf171996United States60BothSecondary3,10 years5Pharmaceutical Company
Caro181997United Kingdom45–64 (55)PrimaryPrimary5 years6Pharmaceutical Company
Ganz192000United States75–84SecondarySecondaryLifetime3University
Goldman211991United States35–84SecondaryBothLifetime5Government
Goldman201993United States35–44SecondaryPrimaryLifetime5Government
Grover221999Canada40–70SecondarySecondaryLifetime3University
Grover242000Canada40–70SecondaryBothLifetime5Pharmaceutical Company
Grover232001Canada40–70SecondaryBothLifetime3Pharmaceutical Company
Hamilton251995Canada30–70SecondaryPrimaryLifetime5Pharmaceutical Company
Hay261991United States35–55SecondaryPrimaryLifetime5Pharmaceutical Company
Huse271998United States45–65SecondaryBothLifetime3Pharmaceutical Company
Johannesson281997Sweden35–70SecondarySecondary5 years5Pharmaceutical Company
Jonsson391996Sweden35–70 (59)PrimarySecondary5 years5Pharmaceutical Company
Jonsson401999Sweden35–70 (60)PrimarySecondary5 years3University
Martens291994Canada45SecondaryPrimaryLifetime5Pharmaceutical Company
Muls301998Belgium60BothSecondary3,10 years5Pharmaceutical Company
Perreault311998Canada44–56–57SecondaryPrimaryLifetime5University
Pharoah321996United Kingdom45–64SecondaryBoth10 years5None
Pickin331999United Kingdom55,58SecondaryBoth5years, lifetime6University
Russell342001Canada45–65SecondaryBothLifetime5Pharmaceutical Company
Szucs361998Germany45–65 (59)PrimarySecondary5 years0University
Szucs352000Germany45–65 (60)PrimarySecondary5 years3University
Riviere381997Canada35–70 (59)SecondarySecondary5, 10, lifetime5Pharmaceutical Company
Van Hout372001Netherlands25–75SecondaryBoth5years, lifetime5University