Number of cases | Loss | Stable | Moderate gain 4%–10% | Substantial gain >10% | p Value linear trend‡ | |
---|---|---|---|---|---|---|
Significantly/marginally significantly different from stable group, *p <0.05; †0.05<p<0.09. ‡Test for linear trend with weight change fitted as a continuous variable. | ||||||
Major CVD | ||||||
<25 | 584 | 1.12 (0.89 to 1.63) | 1.00 | 1.28 (1.06 to 1.55)* | 1.32 (0.99 to 1.76)† | 0.008 |
25–27.5 | 447 | 0.90 (0.67 to 1.20) | 1.00 | 0.93 (0.73 to 1.18) | 1.71 (1.10 to 2.66)* | 0.25 |
27.5–29.9 | 276 | 0.78 (0.56 to 1.08) | 1.00 | 0.90 (0.64 to 1.28) | 1.54 (0.84 to 2.84) | 0.09 |
⩾30 | 147 | 1.25 (0.83 to 1.86) | 1.00 | 0.93 (0.57 to 1.51) | 0.81 (0.34 to 1.94) | 0.54 |
Diabetes | ||||||
<25 | 72 | 0.42 (0.10 to 1.74) | 1.00 | 0.97 (0.54 to 1.73) | 2.02 (0.96 to 4.25)† | 0.005 |
25–27.5 | 99 | 0.88 (0.43 to 1.82) | 1.00 | 1.75 (1.10 to 2.76)* | 2.24 (0.99 to 5.07)† | 0.03 |
27.5–29.9 | 83 | 0.63 (0.33 to 1.21) | 1.00 | 1.15 (0.66 to 2.01) | 0.93 (0.28 to 3.08) | 0.04 |
⩾30 | 73 | 0.52 (0.25 to 1.07)† | 1.00 | 1.40 (0.76 to 2.57) | 2.55 (1.04 to 6.29)* | 0.005 |
Combined end point | ||||||
<25 | 636 | 1.12 (0.83 to 1.52) | 1.00 | 1.22 (1.02 to 1.47)* | 1.35 (1.03 to 1.77)* | 0.001 |
25–27.5 | 514 | 0.92 (0.70 to 1.22) | 1.00 | 1.06 (0.85 to 1.30) | 1.78 (1.19 to 2.68)* | 0.08 |
27.5–29.9 | 334 | 0.77 (0.57 to 1.04)† | 1.00 | 0.98 (0.73 to 1.33) | 1.54 (0.89 to 2.67) | 0.01 |
⩾30 | 199 | 1.01 (0.70 to 1.46) | 1.00 | 1.10 (0.74 to 1.66) | 1.46 (0.79 to 2.70) | 0.10 |