Association between birth weight in mothers (F1) and type 2 diabetes in grandparents (F0)
| Birth weight tertile of mother (range(g)) | Number cases/non-cases | OR (95% CI)* | OR (95% CI)† |
|---|---|---|---|
| *Adjusted for age of grandparent; †adjusted for age and smoking in grandparent. | |||
| Maternal grandmother | |||
| 1 (<3068.2) | 36/2029 | 1 | 1 |
| 2 (3068.2 to 3522.7) | 25/1912 | 0.72 (0.43 to 1.21) | 0.72 (0.43 to 1.21) |
| 3 (3522.8 to 5454.5) | 51/1814 | 1.52 (0.98 to 2.34) | 1.52 (0.98 to 2.34) |
| p for linear trend | 0.046 | 0.046 | |
| (p for non-linear trend) | (0.035) | (0.036) | |
| Maternal grandfather | |||
| 1 (<3068.2) | 44/1717 | 1 | 1 |
| 2 (3068.2 to 3522.7) | 44/1605 | 1.05 (0.69 to 1.61) | 1.06 (0.70 to 1.63) |
| 3 (3522.8 to 5454.5) | 47/1591 | 1.06 (0.70 to 1.61) | 1.08 (0.71 to 1.64) |
| p for linear trend | 0.79 | 0.74 | |
| (p for non-linear trend) | (0.67) | (0.68) | |