Total cholesterol and risk of stroke in quartiles of the cholesterol distribution
| First quartile | Second quartile | Third quartile | Fourth quartile* | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Stroke | Cases | Cases | Cases | Cases | Trend† | ||||
| Odds ratios with 95% CI relative to the first quartile of serum total cholesterol, adjusted for age, sex, and body mass index. Number of control subjects in the respective quartiles were 227, 248, 202 and 228. *Cut off points 5.26, 6.10 and 6.91 mmol/l; †trends: odds ratio per 1 mmol/l increase in total cholesterol; ‡ischaemic stroke including unspecified stroke events. | |||||||||
| All | 80 | 1.0 | 89 | 0.97 (0.68 to 1.41) | 93 | 1.32 (0.91 to 1.90) | 84 | 1.02 (0.70 to 1.49) | 0.96 (0.86 to 1.07) |
| Fatal | 25 | 1.0 | 24 | 0.73 (0.39 to 1.38) | 19 | 0.78 (0.40 to 1.51) | 18 | 0.60 (0.30 to 1.20) | 0.82 (0.67 to 1.00) |
| Non-fatal | 55 | 1.0 | 65 | 1.08 (0.71 to 1.62) | 74 | 1.55 (1.02 to 2.34) | 66 | 1.21 (0.79 to 1.85) | 1.01 (0.90 to 1.13) |
| Haemorrhagic | 14 | 1.0 | 12 | 0.80 (0.37 to 1.79) | 17 | 1.28 (0.60 to 2.75) | 4 | 0.29 (0.09 to 0.92) | 0.78 (0.61 to 1.02) |
| Ischaemic | 51 | 1.0 | 58 | 1.05 (0.68 to 1.61) | 63 | 1.49 (0.98 to 2.30) | 63 | 1.31 (0.85 to 2.02) | 1.05 (0.93 to 1.18) |
| Ischaemic‡ | 66 | 1.0 | 77 | 1.02 (0.69 to 1.51) | 76 | 1.33 (0.90 to 1.98) | 79 | 1.17 (0.79 to 1.74) | 0.99 (0.89 to 1.11) |