Factors associated with use of aspirin and statins. British women aged 60–79 with cardiovascular disease (n=822)
| Number | Percent (95% CI) using aspirin/other antiplatelet | Age adjusted OR antiplatelets (95% CI)* | Fully adjusted OR antiplatelets (95% CI)† | Percent (95% CI) using statins | Age adjusted OR statins (95% CI)* | Fully adjusted OR statins (95% CI)† | |
|---|---|---|---|---|---|---|---|
| *Age added as continuous variable (odds ratio for age group not age adjusted); †simultaneously adjusted for all other factors in first column (age entered as continuous variable all others categorical); ‡mutually exclusive hierarchical categories—that is, women in higher categories cannot appear in ones below; §invasive procedure—CABG, angioplasty, or carotidendarterectomy. | |||||||
| Cardiovascular disease diagnosis‡ | |||||||
| MI | 220 | 51.8 (45.0 to 58.6) | 1 | 1 | 33.2 (27.0 to 39.8) | 1 | 1 |
| Stroke | 109 | 48.6 (38.9 to 58.4) | 0.87 (0.55 to 1.38) | 1.02 (0.59 to 1.77) | 20.2 (13.1 to 29.0) | 0.52 (0.30 to 0.89) | 0.62 (0.33 to 1.15) |
| Angina | 442 | 33.3 (28.9 to 37.9) | 0.46 (0.33 to 0.65) | 0.46 (0.32 to 0.68) | 16.7 (13.4 to 20.6) | 0.40 (0.27 to 0.58) | 0.37 (0.24 to 0.57) |
| Peripheral vascular disease | 51 | 45.1 (31.1 to 59.7) | 0.76 (0.41 to 1.40) | 2.15 (0.22 to 21.14) | 21.6 (11.3 to 35.3) | 0.55 (0.26 to 1.13) | Insufficient data |
| Invasive procedure§ | |||||||
| No | 692 | 43.4 (39.6 to 47.1) | 1 | 1 | 21.2 (18.2 to 24.5) | 1 | 1 |
| Yes | 66 | 56.1 (43.3 to 68.3) | 1.70 (1.02 to 2.84) | 1.29 (0.72 to 2.29) | 48.5 (36.0 to 61.1) | 3.40 (2.02 to 5.70) | 3.41 (1.89 to 6.15) |
| Socioeconomic position | |||||||
| Non-manual | 262 | 42.4 (36.3 to 48.6) | 1 | 1 | 25.6 (20.4 to 31.3) | 1 | 1 |
| Manual | 440 | 39.8 (35.2 to 45.5) | 0.90 (0.66 to 1.23) | 0.87 (0.63 to 1.24) | 20.5 (16.8 to 24.5) | 0.74 (0.51 to 1.06) | 0.75 (0.50 to 1.12) |
| Geographical area | |||||||
| South England | 202 | 36.1 (29.5 to 43.2) | 1 | 1 | 24.8 (19.0 to 31.3) | 1 | 1 |
| Midlands and Wales | 170 | 32.4 (25.4 to 39.9) | 0.85 (0.40 to 1.77) | 0.95 (0.58 to 1.57) | 20.0 (14.3 to 26.8) | 0.74 (0.45 to 1.22) | 0.85 (0.48 to 1.49) |
| North England | 311 | 46.0 (40.3 to 51.7) | 1.52 (1.06 to 2.19) | 1.65 (1.09 to 2.52) | 21.5 (17.1 to 26.5) | 0.82 (0.53 to 1.24) | 0.78 (0.48 to 1.27) |
| Scotland | 139 | 47.5 (39.0 to 56.1) | 1.66 (1.07 to 2.59) | 1.60 (0.95 to 2.72) | 20.8 (14.4 to 28.6) | 0.74 (0.44 to 1.25) | 0.59 (0.31 to 1.10) |
| Date of most recent diagnosis | |||||||
| Before January 1 1995 | 368 | 40.2 (35.2 to 45.4) | 1 | 1 | 19.3 (15.4 to 23.7) | 1 | 1 |
| On or after January 1 1995 | 389 | 42.9 (38.0 to 48.0) | 1.11 (0.83 to 1.48) | 1.31 (0.95 to 1.83) | 24.9 (20.7 to 29.5) | 1.43 (1.01 to 2.02) | 1.57 (1.06 to 2.32) |
| Age group | |||||||
| 60–69 | 347 | 37.8 (32.6 to 43.1) | 1 | 1 | 23.3 (19.00 to 28.2) | 1 | 1 |
| 70–79 | 475 | 43.4 (38.9 to 48.0) | 1.26 (0.95 to 1.67) | 1.20 (0.86 to 1.68) | 20.8 (17.3 to 24.8) | 0.86 (0.62 to 1.20) | 0.75 (0.51 to 1.11) |