Table 2

Serum total homocyst(e)ine and potential confounding variables for ischaemic stroke in the non-cases

Linear regression β coefficient2-150 95% CI p Value
Age (per 5 years)0.040.021 to 0.05<0.01
Systolic BP (per 10 mm Hg)0.0060.006 to 0.0120.03
Diastolic BP (per 10 mm Hg)−0.0002−0.01 to 0.010.97
2-151Alcohol (per SD in ml/day)−0.04−0.05 to −0.03<0.01
Body mass index (per SD in kg/m2)−0.1−0.14 to −0.07<0.01
Creatinine (per SD in μmol/l)0.060.04 to 0.07<0.01
Total cholesterol (per SD in mmol/l)−0.0006−0.01 to 0.010.93
HDL cholesterol (per SD in mmol/l)−0.02−0.03 to −0.007<0.01
2-151Triglycerides (per SD in mmol/l)−0.01−0.02 to 0.020.1
Folate (per SD in μg/day)−0.05−0.06 to −0.04<0.01
2-151B12 (per SD in μg/day)−0.04−0.05 to −0.03<0.01
B6 (per SD in mg/day)−0.02−0.04 to −0.01<0.01
2-152Mean serum tHcy (μm/l) SD
Never smoked11.31.3
Ex smoker11.51.3
Current smoker12.11.4p=<0.01
2-152Mean serum tHcy t test
(μm/l) (SD)
Hypertensive12.11.3
Normotensive11.61.3p=0.01
Manual social class11.81.4
Non-manual social class11.51.3p=0.09
Diabetic10.71.3
Not diabetic11.71.3p=0.01
ECG ischaemia11.81.3
Normal ECG11.71.3p=0.5

  • ↵2-150 Change in homocysteine (natural log) per unit change in risk factor.

  • ↵2-151 Natural log transformed.

  • ↵2-152 Geometric mean.