Table 1

Hazard ratios for association between smoking and mortality from all causes, CVD, CHD, smoking related cancers and alcohol related disease in men

Cause of death (number)		Hazard ratios (95% CI)		p for trend across categories
Smoking category (n)	None (5728)	1–10 (2150)	11–20 (692)	>20 (38)
^1-160All causes (n=861)	1	1.42 (1.21 to 1.65)	2.08 (1.71 to 2.53)	3.39 (1.81 to 6.36)	<0.001
^1-160CVD^1-151(n=339)	1	1.40 (1.09 to 1.78)	2.29 (1.68 to 3.00)	4.18 (1.68 to 10.03)	<0.001
^1-160CHD^1-152 (n=243)	1	1.44 (1.07 to 1.94)	2.67 (1.89 to 3.77)	3.73 (1.18 to 11.80)	<0.001
^1-160Stroke^1-153 (n=66)	1	1.12 (0.65 to 1.93)	1.00 (0.46 to 2.18)	2.96 (0.40 to 21.82)	0.67
^1-150Cancer related to moking^1-154(n=122)	1	2.40 (1.59 to 3.62)	4.01 (2.44 to 6.59)	7.22 (1.74 to 30.08)	<0.001
^1-150Cancer unrelated to smoking (n=185)	1	0.95 (0.68 to 1.35)	1.43 (0.91 to 2.23)	—	0.40
^1-150Respiratory disease^1-164 (n=46)	1	1.91 (1.00 to 3.63)	2.02 (0.79 to 5.16)	9.16 (1.20 to 70.27)	0.021
^1-160Other (n=240)	1	1.17 (0.68 to 2.01)	1.35 (0.62 to 2.95)	3.81 (0.52 to 27.99)	0.27

	None (4927)	1–10 (1724)	11–20 (551)	>20 (31)
^1-165Alcohol related deaths^1-161 (n=114)	1	1.31 (0.84 to 2.02)	1.76 (0.97 to 3.18)	2.28 (0.31 to 16.77)	0.045
^1-165Alcohol related deaths, unrelated to smoking^1-162 (n=97)	1	1.42 (0.90 to 2.25)	1.32 (0.63 to 2.74)	2.67 (0.36 to 19.83)	0.16

↵1-150 Adjusted for systolic blood pressure, BMI, father's social class and year of birth quintile.
↵1-160 Additional adjustment for systolic blood pressure.
↵1-165 Additional adjustment for alcohol consumption.
↵1-151 International classification of disease, ninth revision (ICD-9) codes 390–459,
↵1-152 ICD-9: 410–414,
↵1-153 ICD-9: 430–438,
↵1-154 ICD-9: 140–141, 143–149, 150, 157, 160–163, 188–189,
↵1-164 ICD-9: 460–519,
↵1-161 ICD-9: 141, 143–6, 148–9, 150, 155, 161, 291, 303, 571, 800–999,
↵1-162 ICD-9: 155, 291, 303, 571, and 800–999.