Change in body mass index in men (18 years to recruitment) and mean levels of cardiovascular risk factors at recruitment
| Fifth of change in body mass index (kg/m2) |
Insulin* (geometric mean) (IU/l) | Total triglyceride (geometric mean) (mmol/l) | Glucose* †(mmol/l) |
Diastolic blood pressure (mm Hg) | Systolic blood pressure† (mm Hg) | HDL cholesterol (mmol/l) | Total cholesterol† (mmol/l) |
| −10.5 to +0.86 | 4.02 | 1.23 | 4.70 | 85 | 135 | 1.19 | 6.01 |
| 0.87 to 2.84 | 4.74 | 1.42 | 4.74 | 87 | 141 | 1.13 | 6.24 |
| 2.85 to 4.53 | 5.80 | 1.55 | 4.86 | 89 | 141 | 1.12 | 6.26 |
| 4.54 to 6.63 | 6.43 | 1.76 | 4.85 | 89 | 142 | 1.09 | 6.32 |
| 6.64 to 25.4 | 8.55 | 1.97 | 5.08 | 93 | 145 | 1.05 | 6.26 |
| Mean increase per fifth of change in body mass index, expressed in SD units for each risk factor | 0.24 | 0.20 | 0.15 | 0.14 | 0.11 | −0.10 | 0.05 |
All between group comparisons were highly significant (p<0.001 by one way analysis of variance) as were tests for linear trend.*Diabetics (defined by clinical history or by glucose ⩾7.8 mmol/l) excluded from insulin and glucose analyses. †Evidence of departure from linear trend (p<0.05).