Behavioral teratogenesis: a critical evaluation

Pharmacol Biochem Behav. 1976 Feb;4(2):191-200. doi: 10.1016/0091-3057(76)90014-9.

Abstract

A critical review of some relevant literature concerning the effects of prenatal administration of drugs and several other substances on postnatal behavior. Significant variables and problems in the adequate design of experiments to assess these effects are discussed. Although the evidence concerning prenatal drug effects on behavior is equivocal, sufficient data exist to indicate that this will continue to be a viable and important area of research in the future. Present results demonstrate the complexity of drug interactions with other variables.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amphetamine / pharmacology
  • Animals
  • Antidepressive Agents / pharmacology
  • Behavior, Animal / drug effects*
  • Chlorpromazine / pharmacology
  • Dose-Response Relationship, Drug
  • Dronabinol / pharmacology
  • Embryo, Mammalian / drug effects
  • Embryo, Nonmammalian
  • Female
  • Fetus / drug effects
  • Hypnotics and Sedatives / pharmacology
  • Maternal-Fetal Exchange
  • Meprobamate / pharmacology
  • Methylmercury Compounds / pharmacology
  • Pharmacology*
  • Pregnancy
  • Reserpine / pharmacology
  • Species Specificity
  • Teratogens*
  • Vitamin A / pharmacology

Substances

  • Antidepressive Agents
  • Hypnotics and Sedatives
  • Methylmercury Compounds
  • Teratogens
  • Vitamin A
  • Dronabinol
  • Reserpine
  • Meprobamate
  • Amphetamine
  • Chlorpromazine