Early reportsChildhood social circumstances and psychosocial and behavioural factors as determinants of plasma fibrinogen
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2015, PsychoneuroendocrinologyCitation Excerpt :These include large-scale population surveys linking single measurements of plasma fibrinogen with questionnaire-based self-reported levels of chronic stress, and more focused psychophysiological studies that have measured fibrinogen secretion in response to acute mental stress in laboratory-based experimental settings. Regardless of the study design and the reference population, higher stress was associated with higher fibrinogen plasma concentration (Brunner et al., 1996; Kittel et al., 2002; Steptoe et al., 2003, 2004; Von Känel et al., 2001; Wirtz et al., 2008, 2009). The pathway linking mental stress, fibrinogen, and CVD might therefore appear to be defined: the greater the stress (or poor adaptation to stress), the higher the fibrinogen, and the greater the occurrence of CVD (Austin et al., 2013).
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