The human brain and the way in which it stores and retrieves information is a subject of debate and speculation. There are many possible causes of memory loss or forgetfulness; some factors may be like tiredness, concentration problem, pregnancy, general anxiety, normal ageing and more serious causes are Alzheimer's disease, Parkinson's disease, depression, emotional problems, chronic alcoholism etc. But, Can the cellular phone irradiation be a cause of forgetfulness? This study was particularly designed to investigate the possibilities of association of the common symptom “forgetfulness” among the cellular phone users. The close proximity of the cellular phone to the head causes likely 40–60% energy emitted by the device to be absorbed in the brain. In this study 188 (77.7% male and 22.3% female) cellular phone users in Lucknow city of India were enquired about the association of forgetfulness. They were enquired about their general profile (age, sex etc.), calls detail and health (disease, smoker or non-smoker). The subjects belonged to 14–62 years age range (mean age ± SD; 29.1±9.5). Study revealed that 12.7% (14) subjects were associated to forgetfulness symptom. The frequency of forgetfulness among high user (HU>500 h use in life) and low user (LU<500 h use in life) was found 2.1% and 10.6% respectively. In general it was found that the users, who held cellphone above the 4–5 years, were supplementary associated to the symptoms. This study supported by UP Council of Science and Technology, India. [Ref. CST/D 3558 (2); 31.03.2009].