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Chronic diseaseChair: Dr. Judith MacKay, China
Plenary XI Epidemiology and the control of disease in China, with emphasis on the Chinese Biobank (KSCDC) project
  1. L Li1,2,
  2. Y Guo2,
  3. Z Chen3,
  4. J Chen4,
  5. R Peto3
  1. 1School of Public Health, Peking University, Beijing, China
  2. 2Chinese Academy of Medical Sciences, Beijing, China
  3. 3Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Oxford, UK
  4. 4Chinese Centre for Disease Control, Beijing, China

Abstract

As many other developing countries, China now is facing a double burden of disease as a result of epidemiological transition and Non-communicable disease (NCD) will be a major factor (challenge) which caused quality decline of Chinese population health and growth of economic burden in healthcare. In the era of evidence-based medicine and decision making today, as a developing country, China is lack of local scientific evidence. It will affect the effectiveness of NCD prevention and control.

In such circumstances and on the basis of decade's cooperation and trust with the University of Oxford, we have started China's biobank study Kadoorie Study of Chronic Disease in China in 2004. Kadoorie Study of Chronic Disease in China, an international prospective project, aims to establish the basis of blood-based health database, from the genetic, environmental and lifestyle aspects to deeply study and understand causes, risk factors, pathogenesis, prevalence patterns and trends of major chronic diseases in China (such as stroke, coronary heart disease, cancer, diabetes, hypertension, etc) which endanger health of Chinese population. This study with duration of 15–20 years will also provide scientific evidence for strategy planning of NCD prevention and control, development of new treatment and intervention approach. A total of about 515 000 adults aged 30–79 have been recruited from the general population in 10 geographically defined regions (five rural and five urban) of China, with quite different disease profiles and quite different risk exposures, with extensive data collection by questionnaire, physical measurement and blood sample collection and storage. It is a multi-factor, multi-disease, multi-disciplinary large-scale chronic disease epidemiological study on causes, and is also one of the largest long-term blood-based population cohort studies ever conducted in the world. It is worth mentioning that all gene specimens are kept in China and all associated intellectual property rights are owned by China, which breaks new ground for Chinese and foreign international cooperation.

In this presentation, as a principle investigator of this study in China, I will introduce study design, baseline description and main results of this study as far as now for your information.

  • Epidemiology
  • NCD prevention and control
  • Chinese Biobank Study
  • KSCDC

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