Article Text


Chronic disease
P2-258 Evaluation of the effectiveness of the pharmacotherapy follow-up on the treatment of hypertensive patients: a cohort study
  1. F Rodrigues1,
  2. M Castro2,3,
  3. S Fuchs1,2,
  4. F Fuchs1,2,
  5. L Moreira1,2
  1. 1Postgraduate Studies Program in Health Sciences: Cardiology and Cardiovascular Sciences; UFRGS, Porto Alegre, Rio Grande do Sul, Brazil
  2. 2Division of Cardiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
  3. 3Pharmacy School, UFRGS, Porto Alegre, Rio Grande do Sul, Brazil


Introduction The control rate of hypertension in the population is fair. Pharmaceutical Care is a recent approach, seeking to magnify therapeutic results.

Objective To evaluate the effectiveness of the pharmacotherapy follow-up conducted by the Pharmacist on hypertension management.

Methods The study is a historical cohort with a dynamic population of patients referred to an outpatient hypertension clinic. Patients were followed for 12 months. Those difficult-to-control referred by the physician to pharmacotherapy follow-up were compared with patients under conventional treatment. Endpoints included blood pressure (BP) variation and the rate of control (<140/90 mm Hg). General Linear Model, modified Poisson Regression, and segmented regression were used in the data analysis.

Results Of 993 patients, 150 were referred for pharmacotherapy follow-up. Patients in the pharmacotherapy follow-up were older, with lower education level, longer diagnoses of hypertension and significantly higher levels of BP. The deltas of SBP were 7.4±1.9 vs 10.3±0.8 mm Hg (p=0.16) and diastolic 6.7±1.0 mm Hg vs 5.9±0.4 (p=0.45) for pharmacotherapy follow-up and conventional treatment groups, respectively, adjusted for initial pressure. The control rate was 45.3%, being 28.1% in the exposed and 48.6% in the unexposed (p<0.001). Comparing the BP of the same patients before and after exposure to pharmacotherapy follow-up showed a change in the trend of SBP and DBP (p<0.001).

Conclusion Hypertensive patient difficult-to-control under pharmacotherapy follow-up showed a reduction in BP similar to patients who received only conventional treatment. The study suggests that pharmacotherapy follow-up is effective in the management of selected hypertensive patients.

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