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Chronic disease
P2-214 Rice intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-Based Prospective Study
  1. A Nanri1,
  2. T Mizoue1,
  3. M Noda1,
  4. Y Takahashi1,
  5. M Kato2,
  6. M Inoue3,
  7. S Tsugane3
  1. 1National Center for Global Health and Medicine, Tokyo, Japan
  2. 2Japan Foundation for the Promotion of International Medical Research Cooperation, Tokyo, Japan
  3. 3National Cancer Center, Tokyo, Japan

Abstract

Introduction Refined carbohydrates have been suggested to deteriorate glucose metabolism; however, whether persons with elevated intakes of white rice, a major staple food for the Japanese, experience increased risk of developing type 2 diabetes remains unclear. We prospectively investigated the association between white rice intake and risk of type 2 diabetes.

Methods Participants were 25 666 men and 33 622 women aged 45–75 years who participated in the second survey of the Japan Public Health Center-based Prospective Study and had no prior history of diabetes. We ascertained food intake by using a validated 147-item food frequency questionnaire. ORs of self-reported physician-diagnosed type 2 diabetes over 5 years were estimated by using logistic regressions.

Results A total of 1103 new cases of type 2 diabetes were self-reported. Rice intake was significantly associated with an increased risk of type 2 diabetes in women; the multivariate-adjusted OR for the highest compared with lowest quartiles of rice intake was 1.65 (95% CI 1.06 to 2.57; p for trend =0.005). In men, the association was unclear, although there was a suggestion of a positive association among persons who were not engaged in strenuous physical activity (p for trend = 0.08).

Conclusions Elevated intake of white rice is associated with an increased risk of type 2 diabetes in Japanese women. The finding suggestive of a positive association of rice intake among physically inactive men deserves further investigation.

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