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Epidemiology and policy
P1-278 Associations between socioeconomic position and asthma- findings from a historical cohort
  1. S Patel1,
  2. J Henderson1,
  3. M Jeffreys2,
  4. G Davey-Smith1,
  5. B Galobardes1
  1. 1MRC Causal Analyses in Translational Epidemiology Centre, School of Social and Community Medicine, University of Bristol, Bristol, UK
  2. 2School of Social and Community Medicine, University of Bristol, Bristol, UK

Abstract

Introduction The association between asthma and socioeconomic position (SEP) is not well understood. This study aims to assess the variation in asthma across SEP in a historical cohort before the rise in asthma prevalence.

Methods Students participating in a health survey at Glasgow University from 1948 to 1968 (11 274 men; 3502 women) completed a medical history of bronchitis, asthma, hay fever, eczema/urticaria, and reported early life SEP. A subsample responded to a postal follow-up in adulthood (4101 men; 1411 women) including respiratory diseases and early life and adult SEP.

Results Among men, lower early life SEP was associated with higher risk of non-atopic asthma (asthma without eczema/urticaria or hay fever) (trend aOR=1.25 95% CI 1.05 to 1.48). Lower early life SEP was associated with a lower risk of hay fever (trend aOR=0.76 95% CI 0.68 to 0.85) and atopic asthma (asthma with eczema/urticaria or hay fever) (trend aOR=0.63 95% CI 0.50 to 0.78). No associations were seen for women. Early life SEP, adult household crowding, adult occupation, income and car ownership were not associated with adult onset asthma (onset >30 years) for men or women. Household amenities (<3) in early life was associated with higher risk of adult onset asthma for men (OR=1.48 95% CI 1.07 to 2.05).

Conclusion Lower SEP in early life was associated with a higher risk of non-atopic asthma but a lower risk of hay fever and atopic asthma among men in a cohort that preceded the 1960s rise in asthma prevalence in the UK. Adult onset asthma was associated with early life household amenities but not adult SEP.

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