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Epidemiology and policy
P1-196 The characteristics of reactive oxygen metabolites detected in the serum of early Japanese teenagers
  1. T Kogawa,
  2. S Kurauchi,
  3. M Nishimura,
  4. I Kashiwakura
  1. Hirosaki University, Graduate School of Health Sciences, Hirosaki, Japan

Abstract

Introduction The level of reactive oxygen metabolites in the serum of healthy early Japanese teenagers was analysed to determine the current state of oxidative stress during puberty in early teenagers.

Methods This study enrolled 595 healthy junior high school students from Nanbu town located in Northern Japan. Oxidative stress was evaluated by measuring the serum level of reactive oxygen metabolites (ROM), and antioxidant capacity was evaluated by measuring the serum level of biological antioxidant potential (BAP).

Results Although the ROM level in female students (308.6±63.1 CARR U) was slightly higher than that in the males (299.6±55.2 CARR U), there was no statistically significant difference. The BAP level in males was significantly higher than in females. The level of ROM and BAP detected in males in the first grade were higher than the other grades. Only the first grade's BAP was higher than other grades in females.

Discussion The mean value of ROM in females was higher than the normal (250–300 CARR U). The level of ROM is unrelated to gender and age, and very low in a neonate. The current study found that the level of ROM in males was negatively correlated with their grades. These results suggest that there are some factor(s) that increase the oxidant stress in Japanese junior high school students.

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