20-Year trends in major coronary risk factors in older British men: assessing the impact of medication use
- S. L. Hardoon1,
- P. H. Whincup2,
- S. G. Wannamethee1,
- O. Papacosta1,
- M. C. Thomas1,
- L. T. Lennon1,
- A. G. Thomson1,
- S. Capewell3,
- R. W. Morris1
- 1Department of Primary Care & Population Health, Division of Population Health, UCL Medical School, University College London, Royal Free Campus, Rowland Hill Street, London, UK
- 2Department of Community Health Sciences, St George’s, University of London, Cranmer Terrace, London, UK
- 3School of Population Community & Behavioural Sciences, Division of Public Health, University of Liverpool, Whelan Building (3rd Floor), Brownlow Hill, Quadrangle, Liverpool, UK
Background
Favourable trends in blood pressure (BP) and blood lipids have contributed to the falling incidence of coronary heart disease (CHD) in recent decades. The role of medication in the BP and blood lipid trends is unknown.
Objectives
To investigate the impact of medication on 20-year trends in BP and blood lipids in older British men.
Design
Longitudinal study.
Setting
24 British towns.
Participants
4231 men from a socially and geographically representative cohort of older British men, examined at baseline (1978–80, aged 40–59 years) and …
