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J Epidemiol Community Health 2009;63:2 doi:10.1136/jech.2009.096701b
  • Wednesday 9 September, Parallel session A
  • Life course CVD

Elevated blood pressure in early adulthood as a predictor of later coronary heart disease mortality: up to 83 years follow-up in the Harvard Alumni Health Study

  1. L. Gray1,
  2. I. M. Lee2,3,
  3. H. D. Sesso2,3,
  4. G. D. Batty1
  1. 1
    Medical Research Council Social and Public Health Sciences Unit, Glasgow, UK
  2. 2
    Harvard School of Public Health, Boston, MA, USA
  3. 3
    Brigham and Women’s Hospital, and Harvard Medical School, Boston, MA, USA

      Objectives

      Few studies have examined the association between blood pressure in early adulthood and later coronary heart disease (CHD). In those that have, whether the impact of early adult blood pressure is mediated via blood pressure in middle age or, if it exerts an independent effect, has yet to be tested. We examined these issues using extended follow-up of the Harvard Alumni Study.

      Design

      Cohort study of male University students who had a physical examination at college entry between 1914 and …

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