A novel hypothesis to explain associations of carbon monoxide and nitrogen dioxide with deaths from respiratory disease
- School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; joseph@rad.upenn.edu
- Professor P M Joseph, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; joseph{at}rad.upenn.edu
- Accepted 18 August 2008
The article entitled “Atmospheric pollutants and mortalities in English local authority areas” by Knox analysed a large body of epidemiological data linking various forms of air pollution to the death rates from several diseases, including pneumonia, chronic obstructive pulmonary disease and lung cancer.1
I want to suggest that in some cases the author unknowingly misclassified the exposure, and that the associations with carbon monoxide (CO) and nitrogen dioxide (NO2 …
