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A novel hypothesis to explain associations of carbon monoxide and nitrogen dioxide with deaths from respiratory disease
  1. P M Joseph
  1. School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA;
    joseph@rad.upenn.edu
  1. Professor P M Joseph, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; joseph{at}rad.upenn.edu

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The article entitled “Atmospheric pollutants and mortalities in English local authority areas” by Knox analysed a large body of epidemiological data linking various forms of air pollution to the death rates from several diseases, including pneumonia, chronic obstructive pulmonary disease and lung cancer.1

I want to suggest that in some cases the author unknowingly misclassified the exposure, and that the associations with carbon monoxide (CO) and nitrogen dioxide (NO2 …

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