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Ethnic inequalities in campylobacter infection in Birmingham, UK: descriptive study of notified cases
  1. S Manaseki1,
  2. J Hawker1,
  3. S Ali2
  1. 1Department of Public Health and Epidemiology, University of Birmingham, Birmingham, UK
  2. 2South Birmingham Primary Care Trust, Kings Heath, Birmingham, UK
  1. Correspondence to:
 Dr J Hawker
 Department of Public Health and Epidemiology, University of Birmingham, Birmingham B15 2TT, UK; j.i.hawkerbham.ac.uk

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Food poisoning is the most commonly notified infection in the UK and campylobacter is the most commonly identified microbial cause of those notifications.1 In Birmingham, a multiethnic city in England, there were 1209 statutory notifications with laboratory confirmation of Campylobacter sp in 2001 and, unlike for salmonellosis, there is no evidence of any substantial decrease in cases in recent years. Despite this, the epidemiology of campylobacter infection is poorly understood. We analysed ethnic differences in notification rates by age in Birmingham in response to local observations.

PARTICIPANTS, METHODS, AND RESULTS

In Birmingham, all laboratory diagnosed cases of campylobacter infection are reported by laboratories to the “proper officer”. All such symptomatic cases from 1987 to 1997 (inclusive) were analysed. The validated Nam Pechan computer program2 was used to attach ethnicity to surname and first name of the cases. Names were also visually checked by a South Asian researcher familiar with Muslim, Hindu, and Sikh names. Rates were obtained by averaging the number of infections per year by sex, age group, and ethnicity, and applying Birmingham 1991 census population data.

Altogether 9586 cases were identified (1384 Asian and 8202 non-Asian, a rate of 0.93/1000 population per annum for Asians and 0.90/1000 for non-Asians). Figure 1 shows the pattern of infection rate by age group. Asians under 5 years in both sexes (n = 151) have over 2.5 times higher rates of infection than the non-Asians under 5 (n = 562), (relative risk (RR) = 2.5, 95% confidence intervals: 2.1 to 2.7). The 0–6 months olds in both groups had the highest numbers of infection (77 cases of Asians and 212 of non-Asians), but Asians had proportionally more infections compared with older age groups with a RR for under 6 month olds compared with older ages of 25.9 (18.9 to 35.63) for Asians and 1.19 (1.01 to 1.41) for non-Asians.

Figure 1

Mean annual campylobacter infection rate per 1000 population.

Conversely, non-elderly adults under 60 years of age were significantly at reduced risk in the Asians compared with the non-Asians (RR 15–16 years olds = 0.58 (0.4 to 0.7)). There was no significant ethnic difference in sex distribution, with more male than female cases in both groups. 33.2% (32.2% to 34.2%) of non-Asian cases were notified in the period June to August, a statistically significantly higher proportion than in Asians (28.1%; 25.7 to 30.5).

COMMENT

Our results show that notification rates in young Asian children are more than twice those in non-Asians and a much higher proportion of cases in south Asians occur in infants. Although this result could be influenced by ethnic differences in health seeking behaviour, follow up of symptomatic family members by environmental health officers reduces the likelihood of this being the reason for the age distributions found within ethnic groups. It is important in such studies that the denominator population is reliable, but the use of incidence data from years either side of the 1991 census should have minimised the risk of outdated child denominators.

The bimodal age distribution for non-Asian cases is typical of that for developed countries.3 However, the distribution for Asian cases in Birmingham is more typical of developing countries, such as Bangladesh, where there are very high rates of infection in infants and no secondary peak in adults, because of immunity gained in childhood.4 Many older Asian adults in Birmingham will have been born abroad (97% of >29 year olds were born abroad in 1991 census, although less than 55% of 20–29 year olds). This pattern is consistent with increased exposure of Asian infants to campylobacter, which, if food related, could be attributable to differences in infant feeding, different food providers, food preparation, or food hygiene practices. Travel to higher prevalence countries to visit relatives is common and could also contribute, as could person to person spread from non-toilet trained children.5 Finally, the possibility of differing susceptibilities to severe infection needs to be considered. Our findings should be tested on datasets held by other researchers and, if repeated, merit a case-control study to test potential risk factors.

Acknowledgments

We gratefully acknowledge the support of Jenny Millward and the Infection Control Unit at Birmingham City Council.

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Footnotes

  • Funding: none.

  • Competing interests: none declared.

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