rss
J Epidemiol Community Health 2000;54:293-298 doi:10.1136/jech.54.4.293
  • Research report

Regional variation in incidence and case fatality of myocardial infarction among young women in England, Scotland and Wales

  1. N R Dunna,
  2. A Arscotta,
  3. M Thorogoodb,
  4. B Faragherc,
  5. L de Caesteckerd,
  6. T M MacDonalde,
  7. C McCollumf,
  8. S Thomasg,
  9. R D Manna
  1. aDrug Safety Research Unit, Bursledon Hall, Southampton SO31 1AA, bLondon School of Hygiene and Tropical Medicine, London, cDepartment of Organisational Health Psychology, Manchester School of Management, UMIST, Manchester, dDepartment of Public Health, Greater Glasgow Health Board, Glasgow, eMedicines Monitoring Unit, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital Medical School, Dundee, fDepartment of Surgery, South Manchester University Hospital, West Didsbury, Manchester, gWolfson Unit of Clinical Pharmacology, University of Newcastle, Newcastle upon Tyne
  1. Dr Dunn
  • Accepted 1 October 1999

Abstract

OBJECTIVES To examine the regional variation in incidence and case fatality of myocardial infarction among young women.

DESIGN Cross sectional survey, using population based incidence data.

SETTING England, Scotland and Wales.

SUBJECTS Subjects were women aged 16–44 with a diagnosis of myocardial infarction between 1 October 1993 and 15 October 1995.

OUTCOME MEASURES Incidence of myocardial infarction per 100 000 women years, with case fatality as a percentage of total cases.

RESULTS Incidence of myocardial infarction rose steeply from age 33 upwards, (maximum = 20.2 cases per 100 000 women years at age 44). The adjusted incidence rate for myocardial infarction was 3.7 (95% CI 3.2, 4.2) times greater in Scotland than in southern England. In contrast, case fatality was significantly lower in Scotland: 18.5% (95% CI 13.1%, 25.0%), compared with 31.0% (95% CI 25.9%, 36.0%) in southern England.

CONCLUSIONS The incidence of myocardial infarction varied widely within the United Kingdom. Case fatality variation may reflect differences in ambulance response, or in diagnostic acumen, within the regions.

Footnotes

  • Funding: unconditional grant from NV Organon and Schering AG.

  • Conflicts of interest: none.

This Article

  1. Abstract
  2. Full text
  3. PDF

Responses

  1. Submit a response
  2. No responses published

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Latest infectious diseases and epidemilogy jobs

Ophthalmology Jobs

Show me all >>