Effect estimates (as odds ratios, with 95% CI and p value) from models of perception of a family weakness attributable to heart disease, based on all data and subgroups defined by gender, social class or prevalence of a parental CHD death
| Effect | Subjects included | |||||||
|---|---|---|---|---|---|---|---|---|
| All | Sons | Daughters | Manual | Non-manual | No parental CHD deaths |
⩾1 parental CHD death |
||
| Age4-150 | 0.8 | 0.8 | 0.8 | 1.0 | 0.8 | 0.9 | 0.8 | |
| (0.7, 1.0) | (0.6, 1.1) | (0.7, 1.1) | (0.7, 1.4) | (0.6, 0.9) | (0.7, 1.1) | (0.6, 1.0) | ||
| 0.03 | 0.2 | 0.1 | 0.96 | 0.01 | 0.2 | 0.06 | ||
| Gender4-151 | 1.6 | — | — | 2.0 | 1.4 | 1.5 | 1.6 | |
| (1.2, 2.0) | (1.3, 3.0) | (1.1, 1.9) | (1.1, 2.1) | (1.1, 2.4) | ||||
| 0.0004 | 0.003 | 0.02 | 0.01 | 0.01 | ||||
| Social class4-152 | 0.8 | 0.7 | 0.9 | — | — | 0.9 | 0.7 | |
| (0.6, 1.0) | 0.4, 1.0) | (0.6, 1.3) | (0.6, 1.3) | (0.5, 1.0) | ||||
| 0.09 | 0.04 | 0.6 | 0.5 | 0.07 | ||||
| One parental CHD death4-153 | 3.2 | 3.1 | 3.1 | 2.3 | 3.6 | — | — | |
| (2.5, 4.0) | (2.1, 4.7) | (2.3, 4.3) | (1.5, 3.7) | (2.7, 4.8) | ||||
| <0.0001 | <0.0001 | <0.0001 | 0.0003 | <0.0001 | ||||
| Two parental CHD deaths | 7.9 | 3.5 | 13.0 | 19.3 | 4.3 | — | 2.64-154 | |
| (4.1, 15.2) | (1.1, 11.4) | (5.4, 31.4) | (6.4, 58.7) | (1.8, 10.3) | (1.3, 5.1) | |||
| <0.0001 | 0.03 | <0.0001 | <0.0001 | 0.001 | 0.005 | |||
-
↵4-150 Age effect is for a 10 year difference in offspring age.
-
↵4-151 Gender effect is for daughters relative to sons.
-
↵4-152 Social class effect is for offspring in manual relative to non-manual occupations.
-
↵4-153 Parental CHD death effects (one or two deaths) are relative to offspring whose parents were either alive, or had died from a cause other than CHD.
-
↵4-154 Effect estimate for two parental CHD deaths is relative to one parental CHD death group.
