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Distribution of Paget's disease in England, Wales and Scotland and a possible relationship with vitamin D deficiency in childhood
  1. D. J. P. Barker,
  2. M. J. Gardner
  1. Community Medicine, University of Southampton

    Abstract

    Within England, Wales, and Scotland there are regional variations in hospital discharge rates for Paget's disease (osteitis deformans). Successive cohorts born after the 1880s show a progressive fall in mortality from Paget's disease. Because of the epidemiological similarity between the disease and rickets it is suggested that vitamin D deficiency in childhood may be a predisposing influence.

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